Israel's blistering attack with warplanes and drones against Iran’s nuclear and military structure has sparking an open conflict between the two long-time foes that threatens to escalate.

Hundreds of civilians, mostly in Iran, have been killed by dueling airstrikes despite international pleas for de-escalation.

National security experts warn that Israel's attack on Iran shows why Chinese land and asset purchases in the U.S. pose a significant threat to American security.

Israeli Defence Forces (IDF) claimed to intercept over 100 Unmanned Aerial Vehicles (UAV) launched by Iran in the conflict which began with Israel launching its 'Operation Rising Lion', a massive aerial offensive at key Iranian military and nuclear infrastructure,

Russia has maintained a delicate balancing act in the Middle East for decades, trying to navigate its warm relations with Israel even as it has developed strong economic and military ties with Iran.

Iranian state media report more explosions, with blasts heard in Tehran, as Israel says its air force is hitting military targets.

In response to Israel’s attack, Iran fired back with more than 100 drones. NBC News’ Chief International Correspondent Keir Simmons reports more. Former NATO Supreme Allied Commander retired Gen. Wesley Clark and Senior Fellow at the Carnegie Endowment for International Peace Aaron David Miller join Ana Cabrera to examine the possibility of further attacks.

Markets are having another bout of nerves after Israel bombed Iran, which is believed to have fired back drones in response.