It was long thought that when the membrane of a cell lost its integrity and broke down, the cell would die; cells cannot survive without a cell wall. Many antibiotics target the cell wall of bacteria, ...
A transporter which some bacteria use to recycle fragments of their cell wall has been discovered. Researchers found that the transporter controls resistance to certain kinds of cell-wall targeting ...
Bacteria are evolving to elude our drugs at an alarming rate, so much so that the UN has declared antibiotic resistance a global health emergency with the expectation that it could kill millions upon ...
For bacteria, the first line of defense is the cell wall, which keeps toxins such as antibiotics out. Now, researchers have discovered a key mechanism that bacteria use to build their cell walls, ...
Lehigh's Marcos Pires receives NIH Maximizing Investigators' Research Award (MIRA) for his work on bacterial cell wall changes in response to antibiotics, important for next-generation drug design to ...
Researchers at Umeå University in Sweden published a study “Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall” in mBIO that describes ...
Researchers used advanced imaging techniques to investigate the formation of membrane vesicles in a Gram-positive bacterium, a process that is poorly understood, particularly in bacteria with thick ...
An accumulation of an unexpected intermediate of the peptidoglycan recycling pathway that is able to modulate the synthesis and structure of the cell wall, has been found by researchers at Umeå ...
The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis. Researchers led by Martin ...
Textbook images show peptidoglycan as straight and ordered. The biopolymer peptidoglycan that makes up bacterial cell walls was always assumed to be highly ordered. Textbook images like the one below ...