Genomic instability denotes a heightened tendency for genetic alterations and is recognised as a fundamental hallmark of cancer. Disruption of DNA replication fidelity or repair mechanisms leads to ...
Chromosomal errors are a hallmark of cancer cells. Defects in the genome derived from the incorrect separation of chromosomes (and the DNA packed within) in each division of cells drive tumor growth ...
A discovery upends decades of assumptions regarding DNA replication. The study show that DNA replication in early embryos is different from what past research has taught, and includes a period of ...
THE induction of chromosomal aberrations by exogenous agents, such as viruses, radiation and chemicals, is an area of active cytogenetic investigation. 1 Recently, the psychotomimetic hallucinogen, ...
Stefan Fröhling, M.D., and Hartmut Döhner, M.D. The cause of chromosomal abnormalities remains poorly understood. Studies of various types of leukemia have shown that certain environmental and ...
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