There are a wide variety of protein-based drugs that are used to treat various serious conditions. Insulin is perhaps the most well-known example, which is used for life-saving treatments for diabetes ...

Conventionally, chromatography is used for protein purification, which is extremely expensive. Alternatively, the protein crystallization method could be used to determine protein structure, but this ...

Engineers devised a way to purify protein drugs during manufacturing. Their approach, which uses nanoparticles to rapidly crystallize proteins, could help make protein drugs more affordable and ...

Only a handful of compounds have a knack for crystallizing into a variety of forms, or polymorphs. One of the most prolific, a small molecule known as ROY (so called because it crystallizes in ...

One of the most expensive steps in manufacturing protein drugs such as antibodies or insulin is the purification step: isolating the protein from the bioreactor used to produce it. This step can ...

Within biopharmaceutical companies, crystallography is generally the purview of research scientists involved in structure-based drug design. Its potential for protein purification has been known for ...

A quick, purification-free method was developed by researchers at Institute of Science Tokyo, to capture the detailed 3D structures of flexible sugar molecules. By growing crystals of galectin-10 ...