Thymine metabolism in prokaryotes encompasses both de novo synthesis of deoxythymidine triphosphate (dTTP) via the reductive branch of pyrimidine biosynthesis and salvage pathways that recover ...
DNA replication in eukaryotes is a highly orchestrated process that ensures precise genome duplication before cell division. Initiation occurs at multiple replication origins that are licensed in G1 ...
Replication origins in Trypanosoma brucei integrate multiple features previously described individually in opisthokonts, revealing a unified structural topology built from strand-specific nucleotide ...
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