Power Up! CRISPRi & CRISPRa Tools for Genome-Wide Screening from thescientistllc on Vimeo. Forward genetic screening with CRISPR-Cas9 has created remarkable new opportunities for biological discovery.

CRISPR-Cas9 based technologies have revolutionized many areas of biological research since the discovery that the bacterial immune system could be re-engineered for use in gene editing. One such area ...

CRISPR systems that rely on inactivated Cas enzymes—that is, dead Cas (dCas) enzymes—never looked more alive. They harness the targeting power associated with CRISPR—but not the double-strand cuts. As ...

Genome editing technologies are revolutionizing the life sciences, and CRISPR technology is a key player that regularly updates its multifunctional platform. In select bacteria and archaea, CRISPR ...

CRISPR (cluster of regularly interspaced palindromic repeats) are sequences found in approximately 50% of bacteria and approximately 90% of archaea, providing adaptive immunity against viral infection ...