Several psychiatrists are considering changing guidelines that define depression, due to findings from a new study. Michele Norris talks with Dr. Michael First of Columbia University about expanding ...

Patients are commonly diagnosed with treatment-resistant depression when they do not improve despite receiving two or more pharmacologic treatments for an adequate dose and duration during the same ...

Major depressive disorder affects hundreds of millions worldwide, but a key to understanding its origins may lie in the brain’s immune system. New findings spotlight astrocytes—previously overshadowed ...