Epistatic interactions arise when the combined effect of two or more mutations on an organism’s fitness deviates from the sum of their individual effects. These interactions shape the topology of ...

Epistasis arises when alleles at one locus modify the phenotypic expression of alleles at another, generating non-additive contributions to trait variation. In natural populations, genetic variance ...

Researchers are presenting a novel concept for the mathematical modeling of genetic interactions in biological systems. The team has successfully identified master regulators within the context of an ...