National Academies of Sciences%2c Engineering%2c and Medicine

In Vitro Derived Human Gametes as a Reproductive Technology: Scientific, Ethical, and Regulatory Implications

This workshop will explore the in vitro derivation of human gametes (eggs and sperm) from stem cells. Sessions will consider scientific and clinical goals motivating research in this field, technical ...
Nature

Understanding transgenerational epigenetic inheritance via the gametes in mammals

Reprogramming of the epigenome in mammals occurs in both the germline and the early developing embryo. Some regions of the epigenome appear to escape this process. Parentally imprinted genes are not ...
National Academies of Sciences%2c Engineering%2c and Medicine

In Vitro–Derived Human Gametes as a Reproductive Technology: Scientific, Ethical, and Regulatory Implications: Proceedings of a Workshop

Progress in the in vitro derivation of human gametes (eggs and sperm) continues to advance. In vitro–derived gametes are generated using pluripotent stem cells (PSCs) through a process called “in ...