Repetitive DNA and the D1 protein help matching fruit fly chromosomes recognize one another before eggs form.

A study published July 30 in Science has resolved a 60-year puzzle in genetics — and the answer carries a sobering implication: the routine process that keeps female cells from producing too much ...

Researchers at the Crick have uncovered which genes on the Y chromosome regulate the development of sperm and impact fertility in male mice. This research could help us understand why some men don't ...

Researchers at the Francis Crick Institute studying male mice engineered with different Y chromosome deletions have uncovered which genes on the mouse Y chromosome regulate the development of sperm ...

The humble Y chromosome may be the smallest chromosome in the mammalian genome (and getting even smaller), but it is mighty: genes on the Y chromosome are critical for fertility in males. In a new ...

Understanding gene regulation may be key to interpreting human disease genetics. Genes are regulated in part by stretches of ...

Finding the right drug target remains one of discovery's biggest challenges. Human genetics is helping researchers strengthen ...