Deciphering gene circuits can be tedious and immensely time consuming. Modifying, or designing gene circuits from previously identified pathways presents further challenges. “There are many possible ...

A new design for self-stabilizing, programmable cells While natural cells have evolved to use condensates as a built-in protective system for regulating gene circuit activity, this study is among the ...

Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by delivering a new copy of ...

Over the past 20 years, synthetic biologists have been trying to build biological circuits in living cells to enact specific behaviors such as Boolean logic gates, signal filters, oscillators, state ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing ...

When a gene is turned on in a cell, it creates a ripple effect along the DNA strand, changing the physical structure of the strand. A new study by MIT researchers, appearing in Science, shows that ...

The research team led by Professor Jongmin Kim from the Department of Life Sciences at POSTECH, along with graduate students Hyunseop Goh and Seungdo Choi, has successfully developed the 'Synthetic ...

CAMBRIDGE, MA -- Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by ...