Water molecules help proteins read the human genome, research reveals
In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...
The Scientist12h
A Gene Drive with a Disappearing Act Can Aid Pest Control
A CRISPR-based system that erases itself from fly populations may offer a safer approach to tackling insecticide resistance ...
Yale Scientists Just Cracked the DNA Code That Built the Human Brain
What makes the human brain unique? A Yale study unlocks new insights into genetic changes that shaped our evolution.
Activating complex regions of the genome to treat rare diseases: Researchers identify a a master epigenetic switch
Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...
Gene 'silencer' in junk DNA prevents fatal neurological disease
A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene ...
Scientists Discover Bat Gene That Could Revolutionize COVID-19 Treatment
A study on bat genomes, involving Texas Tech University, discovered genetic adaptations that help bats resist viral ...
CRISPR: From Discovery To Clinic—And Charting A Path Forward
No doubt 2025 will usher in many more advances in CRISPR therapies, thanks to the FDA’s new Platform Technology Designation ...
eLife17h
Genome Restructuring around Innate Immune Genes in Monocytes in Alcohol-associated Hepatitis
The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...
Less, but more: A new evolutionary scenario marked by massive gene loss and expansion
Evolution is traditionally associated with a process of increasing complexity and gaining new genes. However, the explosion ...
Hosted on MSN1h
CRISPR-Cas9 Off-Target Effects: Challenges and Solutions
The CRISPR-Cas9 system offers groundbreaking genome editing capabilities, yet off-target cleavage raises concerns about ...
Armed robbery in Revesby1d
Gene Silencer in Junk DNA Halts Fatal Brain Disease
A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene ...
News Medical on MSN14h
Discovery of gene silencer offers hope for autosomal dominant leukodystrophy
A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene "silencer" that resides in junk DNA is directly sparing people from a devastating ...