Scientists identified 473 human genes that act as genetic “on/off switches,” shaping disease risk through tissue-specific or universal patterns regulated by DNA changes and hormones. Study: ...

Improving the genetic circuits in eukaryotic protein production systems—like human cell lines or Chinese hamster ovaries—has the potential to enhance their value so they may offer not only their own ...

Like switches that turn lights on and off, these regions of nucleotides—called transcriptional enhancers—determine where and when a gene is active, and largely control how much of the corresponding ...

Researchers have identified tiny genetic “switches” that appear to play a surprisingly large role in human language ability.

Scientists have uncovered surprising ways transcription factors, the genetic switches for genes, regulate plant development. Their findings reveal how subtle changes in a lipid-binding region called ...

Some see a finger. Others, a worm. Scientists often call it an antenna. This tiny structure, sticking out from the surface of most human cells, is known as the primary cilium. Though nearly every cell ...

When introducing genes into yeast to make it produce drugs and other useful substances, it is also necessary to reliably switch the production on or off. Researchers have found three gene regulation ...

A research team has developed the "SUPER (Synthetic Upcycling Platform for Engineering Regulators)" platform, which dramatically enhances the performance and stability of gene regulatory devices. This ...

Kobe University bioengineers describe three design principles for efficient and reliably controllable yeast promoters, the genetic switches that regulate the artificially introduced genes necessary ...