New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Gene regulation and chromatin dynamics constitute central themes in modern molecular biology, governing how the genetic blueprint is accessed and utilised during development, differentiation and ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

Retroviruses are viruses that have evolved the ability to write their genetic code into a cell's own DNA. The most ancient ...

Nematologists have long wondered how the the Northern root-knot nematode (Meloidogyne hapla) is able to infect such a wide ...

Chromosome compartment analysis of a cancer cell line cohort reveals different subsets of compartment changes where some track epithelial to mesenchymal transition while others reflect secondary ...

Scientists at St. Jude Children's Research Hospital and Northwestern University identified a previously unknown treatment ...

DNA isn't just a long string of genetic code, but an intricate 3D structure folded inside each cell. That means the tools used to study DNA need to be just as sophisticated-able to read not only the ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...