The major histocompatibility complex (MHC) is encoded by a set of genes that play a key role in the vertebrate adaptive immune system. In humans, these genes encode proteins termed human leukocyte ...
BLEAT is designed to work in three parts. Firstly, it is required to input the transplant recipient’s HLA-B typing information into the software, alongside HLA-B typing information for any potential ...
Researchers found independent associations for 2 HLA class I alleles with an increased risk for allopurinol-induced SCAR: HLA-B*58:01 and HLA-A*34:02. HealthDay News — Two human leukocyte antigen (HLA ...
From studies of genetic polymorphisms and the rate of progression from human immunodeficiency virus type 1 (HIV-1) infection to the acquired immunodeficiency syndrome (AIDS), it appears that the ...
Bone marrow or haemopoietic cell transplantation (HCT) is an effective treatment for multiple blood cancers. However, transplantation comes at a risk of acute or chronic graft-versus-host-disease ...
A study of women and girls in a part of South Africa with high levels of HIV infection has shown that the virus has the ...
Successful engraftment of hematopoietic stem cells from unrelated donors is influenced by disparities between the donor and recipient for HLA-A, B, and C alleles. Disparities between HLA sequence ...
The main aim of this study was to evaluate the significance of HLA-DPB1 expression in acute graft-versus-host disease (GVHD) after hematopoietic cell transplantation ...
Human leukocyte antigen (HLA) typing is important in organ transplantation protocols, as they determine the likelihood of rejection. The HLA system is little understood, however. In simple terms, the ...
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Outcomes of Patients With Double-Hit Lymphoma Who Achieve First Complete Remission Disease relapse remains a major challenge to successful outcomes in patients who undergo allogeneic hematopoietic ...