MIT researchers discovered that the genome’s 3D structure doesn’t vanish during cell division as previously thought. Instead, tiny loops called microcompartments remain (and even strengthen) while ...
University of Wisconsin researchers Sushmita Roy and Erika Da-Inn Lee have developed a new computational tool that maps changes in the genome, ultimately helping researchers see DNA’s 3D organization ...
This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...
Much of the human genome is made of regulatory regions that control which genes are expressed at a given time within a cell. Those regulatory elements can be located near a target gene or up to 2 ...
Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...