In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

He has a background in physics and engineering. He works as a bioinformatics technician in the structural genomics team of Marc A. Martí-Renom at CNAG-CRG (Barcelona), developing tools for the ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

While Hi-C reveals a great deal about the overall 3D organization of the genome, it has limited resolution to pick out specific interactions between genes and regulatory elements such as enhancers.

Chinese researchers have developed a technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis.

The discoveries could also help scientists working on stem cell therapies, since coaxing a stem cell to become a neuron or heart cell requires shifting it from one genetic program to another — each ...

The authors developed a new technique, called Paleo Hi-C, that allowed them to interpret the 3D structure of the mammoth’s genome. They found that the mammoth had 28 pairs of chromosomes, ...