This happens even when the same programs or executable files have run on the same or other 64-bit Windows 11/10 PCs. The program or feature cannot start or run due to incompatibility with 64-bit ...

What's truly miraculous in this age of disposable software is that the original 16-bit Winfile and Progman binaries run unmodified on Windows 10 64-bit, if you also have the required DLLs.

I have the pleasure of supporting an ancient 16 bit program for a client. It worked fine on their old server running Windows Server 2003 (32 bit) but will not work now that a new 2008 R2 server ...