The immune system’s capacity to distinguish self from non-self is in large part mediated by immunoglobulins, with IgG playing a pivotal role in both protective and pathological responses.

Immunoglobulins, or antibodies, are produced by white blood cells. They help your body defend against infections and conditions like cancer. Tests measure them and help diagnose these medical ...

From this core mechanism Fc engineering has evolved over time into the "engine" of therapeutic antibody development. It ...

A comprehensive study mapped the dynamic glycosylation landscape of rat serum proteins, uncovering sex- and time-dependent ...

A Japanese research team has uncovered how sugar chains (glycans) modifications dynamically regulate the structure and function of human immunoglobulin G (IgG) antibodies. By integrating nuclear ...

This is a preview. Log in through your library . Abstract Idiotypy has been studied in antibodies against a protein antigen: hen ovalbumin. Various fractions of antisera to hen ovalbumin have been ...

Daniel R. Lucey, Stephen A. McGuire, Mario Clerici, Kevin Hall, Jean Benton, Clifford A. Butzin, William W. Ward, Gene Shearer, R. Neal Boswell and Craig W. Hendrix β₂-microglobulin levels were ...

The herpes IgG test is a blood test used to diagnose herpes simplex virus (HSV). This includes HSV-1, the type most commonly linked to cold sores, and HSV-2, the type mainly associated with genital ...

A positive rubella IgG test indicates immunity to rubella, meaning that the pregnant person and the fetus cannot contract this virus. If a person contracts rubella, also known as German measles, ...

Details and references regarding individual diseases are provided in the Supplementary Appendix. CIDP denotes chronic inflammatory demyelinating polyneuropathy, Covid-19 coronavirus disease 2019, and ...