Cells are, at a fundamental level, protein-production facilities. So naturally, when researchers need to make some particular protein, they should let the cells do the work for them. But living cells ...

Cell-free, in vitro protein expression is a welcome alternative to time-consuming cell-based systems and appeals to scientists interested in toxic, insoluble, or rapidly degraded proteins incompatible ...

In a recent study published in Nature, a group of researchers explored how the incorporation of N1-methylpseudouridine (1-methylΨ) into messenger ribonucleic acids (mRNAs) affects ribosomal ...

Progress in the in vitro derivation of human gametes (eggs and sperm) continues to advance. In vitro–derived gametes are generated using pluripotent stem cells (PSCs) through a process called “in ...