Novel nephron organoids that can be fine-tuned to represent the proximal convoluted tubule or loop of Henle have been ...

The kidney carries out important functions via microscopic functional units called nephrons. Researchers are investigating which factors control the formation and function of specific segments of the ...

A pair of USC Stem Cell mouse studies detail how progenitor cells self-renew, differentiate, and aggregate into early kidney structures, offering insights for the creation of stem cell-based ...

In videos created by the Hughes Lab to visualize the process, adjacent nephrons form one after the other, as if they were following a beat. “It’s still a hypothesis,” adds Hughes, “but we think that ...

A group of essential signaling molecules known as the Wnt pathway emerged early in the evolution of multicellular life. Scientists have been studying Wnt actions for four decades to comprehend its ...

The gene KCTD1 directs production of a protein that functions in the kidney to maintain a normal balance of magnesium and calcium in blood. Loss of KCTD1 impairs the ability of the kidney to properly ...

Kidneys form as their tubules branch, a variable process that leads to some people's kidneys having nine times as many ...

For most children with renal masses, the standard of care has long been to remove the entire affected kidney- which is the protocol for Wilms tumor, the most common kidney cancer in children. But is ...

A scoring criterion which can distinguish between benign and malignant tumors in pediatric patients with renal masses could help determine if they can benefit from partial rather than radical ...