Results demonstrated an incidence rate of 391/100,000 person years was calculated based on the 163 patients who were hospitalized with lactic acidosis during the follow-up period. According to results ...

This is a preview. Log in through your library . Abstract Lactic acidosis is occasionally responsible for metabolic acidosis in diabetics. It may occur in the presence of normal blood levels of the ...

Metformin is one of most commonly prescribed medications for the treatment of type 2 diabetes mellitus. Metformin exerts its activity by increasing peripheral glucose uptake and utilization, and ...

Lactate is the end product of the cytosolic metabolism of glucose, and its accumulation in the blood signals an increase in production or a decrease in utilization, or both. The liver is a major site ...

A 58-year-old woman who has adult-onset diabetes mellitus, hypertension, and hyperlipidemia was taking simvastatin (Zocor) 40 mg, glyburide (Diabeta) 20 mg, metformin (Glucophage) 850 mg t.i.d., ...

HONG KONG — A new Japanese and U.S. collaborative study showing that inhibition of the oxygen sensor prolyl hydroxylase domain-containing protein 2 (PHD2) in the liver enhanced uptake of lactate for ...

Usually nothing to worry about, lactic acid is produced as a result of anaerobic metabolism – the process during which the body produces energy without oxygen. Here’s more information about lactic ...

A 49-year-old woman was admitted to the Mount Sinai Hospital because of coma and hypothermia. The diagnosis of diabetes mellitus had been established 4 years previously. Initial treatment of the ...

A 41-year-old man presented with fevers, weakness, dizziness, and nausea. He had hypotension (87/53 mm Hg), tachycardia, and lactic acidosis. Computed tomography was performed (see images). The ...

Lactic acidosis represents a challenging metabolic complication in patients with haematological malignancies. Notably, type B lactic acidosis occurs in the absence of hypoxia and is associated with ...