A team of UK-based scientists has recently developed an allele-specific probe polymerase chain reaction method that can accurately detect different variants/lineages of severe acute respiratory ...

Pneumonia remains one of the leading causes of death in low- and middle-income countries, where access to advanced medical technologies is limited. According to the World Health Organization, acute ...

Following adeno-associated virus (AAV)-mediated transduction, cellular RNA preparations can be contaminated with AAV single-stranded DNA. The single-stranded DNA genome of recombinant AAV vectors can ...

PCR is a technique used to amplify target DNA in a sample. It’s a well-known method that has undergone numerous modifications to enhance its capabilities. This year, it’s turning 40 years old. PCR has ...

When it comes to detecting rare cancer-causing mutations, both sensitivity and specificity matter. In the past few years, digital PCR (dPCR) has captured the attention of researchers and clinicians ...

Chemists at Northwestern University have set a DNA detection sensitivity record for a diagnostic method that is not based on PCR -- giving PCR a legitimate rival for the first time. EVANSTON, Ill. --- ...

Currently established rapid methods for sterility testing of advanced therapy medicinal products (ATMPs) are mostly based on growth-based processes or the detection of metabolic activities. However, ...

A digital polymerase chain reaction (dPCR) technique for screening malaria parasite genomes will help identify when they have mutations that allow them to dodge detection by some rapid tests, shows a ...

The role of diffusion weighted magnetic resonance imaging for the characterisation of mediastinal lymphadenopathy. Accurate and precise targeted NGS with BRCA MASTR Plus Dx for BRCA1 and BRCA2 ...

PCR genetic analysis has been in the spotlight since COVID-19, but light is now further facilitating PCR-free methods. Osaka Metropolitan University scientists have developed a light-induced DNA ...