A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...
The structural and functional characteristics of mitochondria shape their role as signaling organelles, with far-reaching ...
A previously unknown type of DNA damage in the mitochondria, the tiny power plants inside our cells, could shed light on how our bodies sense and respond to stress. The findings of the UC ...
Mitochondrial DNA has long been treated as a workhorse record of cellular history, but new research suggests it also hides a subtle and previously overlooked form of damage. By uncovering this cryptic ...
Research led by the Max Planck Institute for Biology of Aging in Cologne reports that misincorporation of ribonucleotides into mitochondrial DNA (mtDNA) initiates an inflammatory cascade. Mitochondria ...
Researchers identified a new, sticky form of mitochondrial DNA damage that builds up at dramatically higher levels than in nuclear DNA. These lesions disrupt energy production and activate ...
Researchers from Karolinska Institutet have discovered how mammalian cells prevent the gradual buildup of harmful mutations in mitochondrial DNA, the small but vital genome that powers every cell. The ...
Researchers have discovered a key molecular process that may contribute to chronic inflammation as we age. If this process can be accurately targeted, it could unlock ways to stay healthier in our ...
The tiny little powerhouses of our cells: mitochondria, are unique among organelles because they carry their own tiny little genomes. This genetic material is separate from the rest of our genomic DNA ...
Mitochondria act as energy factories in cells and have their own, separate DNA. Mutations to mitochondrial DNA (mtDNA) have been observed in cancer, but it has been unclear how these changes might ...
As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health. This has drawn attention to the need to extend "healthspan," the ...