Mechanisms of control of mitochondrial DNA transcription The nearly 10 million billion mitochondria found in the human body arose nearly two billion years ago when a eukaryotic cell precursor engulfed ...

Wenwen Li and colleagues started to investigate the role of mitochondrial transcription in cognition in the hippocampus of young and aged mice. Li et al. found a novel coupling mechanism ...

Transcription is the process by which an RNA polymerase synthesizes ribonucleic acid (RNA) using deoxyribonucleic acid (DNA) as a template. Knockout of mitochondrial transcription elongation ...

Now, plant molecular biologist Shin-ichi Arimura of the University of Tokyo and colleagues have filled this gap, creating plant-friendly mitoTALENs—mitochondria-targeting gene editing tools based on ...

“This is a straightforward and clear story,” said Cole Haynes, who studies mitochondrial dysfunction at Memorial Sloan Kettering Cancer Center ...

Interestingly, mammalian cells contain genetic information (DNA) in two compartments, the nucleus and the mitochondria. These DNA molecules are a blueprint, carrying the instructions required for our ...