The scientific terms for these two determinants are pharmacokinetics and pharmacodynamics, and both are critical considerations in the field of pharmacogenomics. Pharmacokinetics encompasses four ...

Pharmacogenomics (PGx) is a subset of precision medicine that focuses on the genetics behind different pharmaceutical interactions, toxicities, and efficacies. PGx improves drug discovery and ...

The study of molecular genetic variation is not new. As early as 1979, Jeffreys 3 suggested that as many as one in every 100 bases within the genome exhibit variance. Indeed, molecular geneticists ...

Typical approaches from pharmacogenomics combined with systems biology and bioinformatics support these routes (simulations, metagenomics and metabolic network modeling), as well as the patient ...