Addgene is launching the service with more than 27,000 plasmids available in the Transfection-Ready format across three of the most-requested areas of its collection: CRISPR, imaging and reporters, ...

Ever since the discovery of DNA’s double-helix structure, life scientists have been interested in somehow introducing foreign nucleic acid molecules into a host cell and expressing the genes encoded ...

Plasmids are essential for the development of viral vectors used to manufacture novel gene therapies and viral vaccines. Aldevron is supporting the innovation of drug developers in this space by ...

Plasmid DNA can be used across an extensive range of applications. Therefore, ensuring the supply is purified in the right way is crucial for every given situation. Analytik Jena‘s CyBio FeliX Liquid ...

The Gibco™ Expi293™ Expression System is a high-yield transient expression system based on suspension-adapted Human Embryonic Kidney (HEK) cells that are highly transfectable and that will grow with a ...

Plasmid extraction—a process that involves lysing host cells and separating circular plasmid DNA from chromosomal DNA, proteins, and other cellular debris—is an essential technique across molecular ...

Transfection alters the genetic makeup of eukaryotic cells by introducing foreign nucleic acids, including DNA, RNA, and small noncoding RNAs such as siRNA, shRNA, and miRNA. Scientists use ...

Hinnah Campwala (left) is a Principal Scientist in the Cell Biology Development Group at Sartorius BioAnalytical Instruments (Michigan, USA). With a background in drug discovery and immune cell ...

Scaling a viral vector process from benchtop to clinical supply isn't a bigger version of monoclonal antibody (mAb) manufacturing, but an entirely different analytical challenge. Cell and gene therapy ...

An essential step in the development of almost any molecular therapeutic is the transfection of plasmids containing the therapeutic sequence into cells for delivery or production of the active ...