The prion protein forms functional condensates that are enriched at cell-cell interfaces. However, long exposure to copper ions/hydrogen peroxide that result in oxidative stress, triggers a ...
Yeast prions are increasingly recognised as pivotal agents in non-Mendelian inheritance, whereby protein conformations rather than nucleic acids dictate heritable traits. In Saccharomyces cerevisiae ...
In a new study, researchers from Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, ...
After an epic series of experiments, a group of researchers has observed and reproduced what could be the spontaneous generation of prions--rogue misfolded proteins that have been implicated in the ...
A new study by SISSA and the University of Campania 'Luigi Vanvitelli' delves into the dynamics that cause prion proteins to take on the pathological form responsible for serious neurodegenerative ...
In a new study, researchers have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, they say, reveals the mechanism for how prions can jump ...
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