With a newly developed method that compares AI-generated protein sequences with naturally occurring ones, function- and ...
Researchers used cryo-EM to study how the HIV enzyme integrase arranges in 3D to slip its DNA into the host genome and pack ...
Proteins are the end products of the decoding process that starts with the information in cellular DNA. As workhorses of the cell, proteins compose structural and motor elements in the cell, and they ...
A quick, purification-free method was developed by researchers at the Institute of Science Tokyo, to capture the detailed 3D ...
Virtual screening methods fall broadly into two categories: ligand- and structure-based. Ligand-based virtual screening doesn’t require a target protein structure, Instead, it leverages known active ...
The developers of OpenFold3 have released an early version of the tool, which they hope will one day perform on par with DeepMind’s protein-structure model.
Proteins play a key role not only in the body, but also in medicine: they either serve as active ingredients, such as enzymes ...
The open-source AI model improves transparency in predicting how proteins interact with other molecules, which could speed up drug discovery.
That problem is why, even though we’ve had success finding enzymes that break down common plastics like polyesters and PET, they’re only partial solutions to plastic waste. However, researchers aren’t ...
Could yeast and humans be any more different? Going by looks alone, probably not. But peering into our genomes reveals ...
An international research team has determined the first high-resolution structures of the herpes simplex virus origin-binding ...
Scientists have for the first time looked deep into the protein structure that may determine our vision - and discovered that it is much more dynamic than previously thought. RBP3 not only changes its ...