When machine learning is used to suggest new potential scientific insights or directions, algorithms sometimes offer ...

With MassiveFold, scientists have unlocked AlphaFold's full potential, making high-confidence protein predictions faster and more accessible, fueling breakthroughs in biology and drug discovery. Brief ...

The drug development pipeline is a costly and lengthy process. Identifying high-quality "hit" compounds—those with high ...

Proteins, the natural molecules that carry out key cellular functions within the body, are the building blocks of all diseases. Characterizing proteins can reveal the mechanisms of a disease, ...

Gero, a biotechnology company developing novel therapeutics for aging and chronic diseases, has released ProtoBind-Diff, a novel masked diffusion language model that generates drug-like molecules for ...

This review provides an overview of traditional and modern methods for protein structure prediction and their characteristics and introduces the groundbreaking network features of the AlphaFold family ...

Researchers at the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University observe and model how the enzyme ADAR1 interacts with double-stranded RNA, which may be useful for future cancer ...

Conserved sequence motifs within intrinsically disordered protein regions act as evolutionary units that support phase separation and membraneless organelle formation.

Researchers in Göttingen, Germany, have elucidated the structure and function of otoferlin, a protein that plays a crucial ...

New imaging reveals cancer-linked ADAR1 enzyme structure, potentially enabling targeted therapies by combining HS-AFM and 3D modeling techniques. (Nanowerk News) An enzyme type noted in several ...