Reducing RAD23A levels helped nerve cells better handle toxic TDP-43 protein clumps, improving survival and function in an ALS mouse model.
Membrane protein targeting and insertion is a fundamental process in cellular biology that ensures proteins are correctly delivered to, and integrated within, the lipid bilayer. Proteins destined for ...
A research team at the University of California San Diego has discovered a novel and promising method of treating arrhythmogenic cardiomyopathy (ACM), a rare inherited heart disease that can strike ...
Northwestern Medicine scientists have zeroed in on a cellular gatekeeper that may hold promise for treating abnormal protein ...
Targeted protein degradation presents a promising strategy to address antimicrobial resistance, focusing on innovative ...
Targeted protein degradation (TPD) is transforming drug discovery by leveraging the cell’s natural protein disposal systems to eliminate disease-causing proteins. Innovators are making rapid and ...
A Purdue University team has discovered a new therapeutic target for triple-negative breast cancer. The research, led by Kyle ...
Proteins circulating in the blood could accelerate the aging of blood vessels and increase silent cardiac risk.