Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

In 1997, Sanger, Nicklen and Coulson described a method for determining DNA nucleotide sequences. 1 Nearly five decades later, Sanger sequencing remains an entrenched technology for targeted ...

Due to its high accuracy and fast, simple workflow, capillary electrophoresis (CE) is a foundational technology for clinical applications. CE is an invaluable tool used to detect genetic variations ...

The last three years have been anything but static for next-generation sequencing (NGS) companies. Several competitors have launched new sequencing technologies that have taken direct, and often ...

Short-read sequencing built the modern genomics era. Illumina platforms, generating millions of short DNA fragments in parallel, became the workhorse of most laboratories from the late 2000s onward.

The Sanger vs next-generation sequencing (NGS) question is not about which method is better. Sanger sequencing did not lose to NGS; it just wasn't the answer for questions involving more than a few ...