The metazoan cGAMP-activated cGAS–STING innate immunity pathway is triggered in response to genomic instability and DNA damage, thereby providing host defense against microbial pathogens. This pathway ...
Second messengers, including cAMP, cGMP and Ca 2+ are often placed in an integrating position to combine the extracellular cues that orient growing axons in the developing brain. This view suggests ...
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