Affecting both people and animals, prion diseases are degenerative brain disorders that can debilitate or kill their victims. The most common form of prion disease affecting humans is sporadic ...

August 24, 2010 — A novel sporadic prion protein disease, variably protease-sensitive prionopathy (VPSPr), with distinct features has been described as the first new prion disease since sporadic ...

Throughout Season 10 of Chicago Med, Dr. Caitlin Lenox (Sarah Ramos) has emerged as one of Gaffney's finest recruits. As she continues to expertly call the shots in the Emergency Department, viewers ...

The most common cause of inherited prion diseases is the E200K mutation of the prion protein (PrP). It is often thought that this mutation causes disease by making PrP more susceptible to misfolding ...

A new epigenetic editing tool shows promise as a therapy for prion disease. The approach for silencing prion protein (PrP), is both specific and can lead to wide-spread knockdown expression of PrP ...

Drug development is typically slow: the pipeline from basic research discoveries that provide the basis for a new drug to clinical trials to production of a widely available medicine can take decades.

(Boston)—Genetic prion disease generally manifests with cognitive difficulties, poor muscle control and abrupt jerking movements of muscle groups and/or entire limbs. The three major phenotypes of ...