Clinical trials offer a slew of benefits: optimal dosage ranges, identified potential side effects, and efficacy data. If approved by the FDA, clinicians leverage the insights from Phase III trials to ...

America prescribes more than 4 billion drugs each year, and half of them aren't even working. The CEO of a leading pharmacogenomics firm shares his thoughts about a new cure to this issue and what it ...

As genomic medicine evolves, health systems are embedding pharmacogenomics into pharmacy operations, not only as a research function but as a clinical asset to personalize patient treatment and reduce ...

In this blog, I will delve into some of the growing acceptance in healthcare to innovative approaches in various countries, and how a database will facilitate analysis and interpretation for all. The ...

Omeprazole, the prototype drug of PPIs, is metabolized primarily by CYP2C19 to 5-hydroxyomeprazole. 5-hydroxyomeprazole is then transformed into 5-hydroxyomeprazole sulfone by CYP3A4. Omeprazole is ...

In a report recently published in the American Journal of Health-System Pharmacy, the Ochsner Health system investigates the multifaceted implementation of pharmacogenomics—a rapidly evolving field ...

In a recent article published in the Genes Journal, researchers discussed the significance of pharmacogenomics-based studies in the research for personalized therapeutics for dementia, including drugs ...

The ultimate goal of pharmacologic management of disease is to maximize the efficacy of therapeutic agents while minimizing their toxicity; the need to attain this goal is inherently more pronounced ...

Pharmacogenomics has had rapid implementation over the past decade, with recent growth in application in oncology, mental health, solid organ transplantation, and more. There has been much focus on ...

Variability in drug response to many therapeutic drug classes is well recognized. These interpatient differences have been seen for both drug efficacy and adverse effects. Pharmacogenomics (Pgx) aims ...

In this table the most frequent alleles are presented that are important for the clinical practice [11,16]. Data on rare, less frequent alleles can be found at [101]. CYP2C19-mediated interactions ...