Again, the association between the COX pathway and LT synthesis may also indicate the role played by the latter in causing inflammatory lung damage in severe COVID-19.

A baseline study revealed that the volunteers' immune cells rapidly initiated production of COX-2, 5-LOX and FLAP enzymes upon pro-inflammatory stimulation.

Overexpression of COX-2 or 5-LOX increases levels of PGE-2 and 5-HETE, respectively. Elevated levels of VEGF are common in patients with non- small cell lung cancer (NSCLC).

Conclusion The combination of BC and GP downregulates the 5-LOX inflammatory pathway by inhibiting activation of MG and promotes M1-to-M2 polarization of MG.

Advances in Horticultural Science, Vol. 34, No. 1S, Special issue on postharvest (2020), pp. 97-108 (12 pages) The patterns of volatile organic compounds (VOCs) emission and the expression of genes ...

The early phase, peaking in 0.1–1 h after the MeJA treatment, was characterized by emissions of lipoxygenase (LOX) pathway volatiles and methanol. In the subsequent phase, starting in 6–12 h and ...