In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

A team of investigators from Dana-Farber Cancer Institute, The Broad Institute of MIT and Harvard, Google, and Columbia University have created an artificial intelligence model that can predict which ...

New AI model takes minutes rather than days to predict how a specific DNA sequence will arrange itself in the cell nucleus.

Shorter telomeres are linked to higher risks of stroke, dementia, and depression, but lifestyle factors may help counteract these effects. Shorter telomeres, the protective caps on chromosomes, are ...

By 8,000 years ago, in the earliest European sheep populations, the team found evidence that farmers were deliberately selecting their flocks—in particular for the genes coding for coat color.

Maternal DNA, particularly the X chromosome, significantly influences a baby’s brain development and aging. Genetic variations and maternal vitamin D levels during pregnancy impact cognition, memory, ...

Older female mice show poor spatial memory when their paternal X chromosome is inactive ... to the genome that do not alter the DNA sequence but regulate gene expression. It prevents females ...

Female mammals typically carry two X chromosomes ... genes themselves, she explained. This also enabled the team to pinpoint differences in epigenetics — chemical tags that attach to DNA ...

with some showing considerable or complete skew of the X chromosome that remains active. Parent-of-X origin can modify epigenetics through DNA methylation and possibly gene expression; thus, mosaicism ...

"Given the fact that the X chromosome is enriched for brain-related genes, it became very important for us to know what roles it might be playing in brain aging," said Samira Abdulai-Saiku ...