Researchers developed an epigenetic editing approach to silence the PCSK9 gene, achieving long-term cholesterol reduction ...

Epigenetics involves genetic control by factors ... Two examples of these types of drugs are 5-azacytidine and 5-aza-2′-deoxycytidine (Egger et al., 2004). These medications work by acting ...

Epigenetics can contribute to understanding interindividual differences in the expression of drug transporters and drug-metabolizing enzymes, thus providing an additional basis for the explanation ...

Epigenetics is the study of various heritable alterations ... “There are these clinically approved drugs that can work and be tolerable enough in certain circumstances, but they're very pleiotropic.

Making use of this complementary regulation system raises the prospect of developing therapies based on "epigenetic drugs" that target DNA and RNA at the same time. The scientists hope to be able ...

The new drug strategy is the culmination of an intensive investigation into ways to target and block proteins that facilitate cancer-specific epigenetic changes in cells. Epigenetics ("on top of ...

A study reveals DNA and RNA epigenetics work together as a complementary system for precise gene regulation, crucial for cell ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

The work adds to a growing body of research investigating whether parents' life experiences can be passed on to future generations through these epigenetic changes. Related: Father's use of diabetes ...