Purpose. The effects of genetic polymorphisms on the pharmacokinetics of calcineurin inhibitors were examined. Pharmacogenetics examines the relationship between single-gene polymorphisms and the ...

A research team performed a large-scale genome analysis of Japanese and European populations and discovered gene regions (genetic polymorphisms) related to allergic sensitization. Some of these ...

The purpose of this review is (1) to systematically present data relating AGTR1 gene polymorphisms in association with hypertension; and (2) to perform a meta-analysis of association studies of ...

A genetic causal link between rheumatoid arthritis (RA) and an increased risk of traumatic and osteoporotic fractures ...

Future research will focus on applying this approach to study genetic polymorphisms, the variations in DNA sequence that contribute to individual differences and disease susceptibility.

Single nucleotide polymorphisms occur normally in human DNA and are the most common genetic variation. They occur when there is a difference in one nucleotide—the most basic unit of DNA.

The study titled “Consanguine Marriage leads to Hierarchical Imbalance of ABO and STR Frequency and affects the Genetic ...

They then integrated these findings with GWAS data on a European population of 25,032 individuals to identify genetic polymorphisms related to allergic sensitization. The research team found 18 ...

The following is a summary of “High Density Lipoproteins Associate with Age-Related Macular Degeneration in the All of Us Research Program,” published in the January 2025 issue of Ophthalmology by ...

Candidate genetic variants included in a genetic risk algorithm may not meet standards of reasonable clinical efficacy in identifying opioid use disorder risk, according to a study published in JAMA ...

Genetic testing and analysis of genetic markers called single nucleotide polymorphisms (SNPs), which represent individual variations in DNA sequence data, can help researchers directly infer ...

Humans are continuously exposed to various environmental allergens (antigens), such as pollen, food, and dust mites. In certain individuals, their immune system recognizes common environmental ...