Genome editing-based therapies typically aim to treat disease by correcting underlying genetic mutations in patient's cells.

A study has traced thousands of conserved regulatory elements back 300 million years, revealing deep principles of plant genome evolution—a discovery that could pave the way for more precise ...

By Hugo Francisco de Souza Trained on genomic data spanning the tree of life, Evo 2 reveals how artificial intelligence can ...

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that future therapies might exploit to collapse tumors.

DNA methylation is a highly studied epigenetic modification that regulates genome function and plays key roles in development and disease 1. It is linked to a broad range of conditions, including ...

For decades, scientists believed a fertilized egg’s DNA began as a shapeless mass, only organizing itself once the embryo switched on its genes. But new research reveals that the genome is already ...

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

A study published today in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, ...

A team of international scientists, including researchers at the Donald Danforth Plant Science Center, reports a major advance in sorghum genomics: a powerful new resource designed to speed discovery ...

DNA methylation is an epigenetic modification crucial to normal development, with its dysregulation leading to various diseases including cancer. As interest in epigenomics grows, an innovative ...

Most lethal mutations in wild fruit flies are driven by newly transferred jumping genes, not small DNA errors, according to a ...