This is an important and solid study that examines the role of TFAM, a protein that helps maintain mtDNA, in mtDNA mutator mice. The authors have demonstrated that TFAM's counteractive role in mtDNA ...

In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

Researchers have revealed new details about the CRISPR-Cas5-HNH/Cascade complex, a variant of the type I-E CRISPR-Cas system, ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Mitochondrial DNA (mtDNA) is actively removed during spermatogenesis in a conserved process that enforces the uniparental ...

The provision will enable whole genome sequencing for neonatal and paediatric patients in intensive care units within 48 ...

Biomedical engineers at Duke University have demonstrated a promising new approach that could be used to treat a rare and ...

A team led by University of Pittsburgh School of Public Health geneticists has shown, for the first time, that a gene ...

What makes the human brain unique? A Yale study unlocks new insights into genetic changes that shaped our evolution.

Chromosome instability describes the increased probability of acquiring chromosomal aberrations due to defects in processes such as DNA repair ... challenging due to genomic heterogeneity.

Genomics is the study of the full genetic complement of an organism (the genome). It employs recombinant DNA, DNA sequencing methods, and bioinformatics to sequence, assemble, and analyse the ...