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To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...
Illustration of RNA bound to zinc-finger antiviral protein (ZAP). ZAP binds cytosine and guanine dinucleotides in viral RNA to prevent the virus from replicating and spreading infection.
Illustration of messenger RNA (red) produced from a DNA strand (purple). Credit: Juan Gaertner/SPL. The conventional view of RNA casts the molecule in a supporting role — the intermediary ...
To create the new editing tool, called REPAIR, the researchers combined CRISPR-Cas13 with a protein called ADAR. It works this way: the Cas13 enzyme is programmed to target a specific RNA sequence ...
The approval of yet another RNA-based vaccine for COVID-19 might not seem momentous. But the endorsement last week by Japanese authorities of a jab against SARS-CoV-2 constructed using a form of ...
An illustration of RNA. (Illustration: Christine Daniloff/MIT) “You could use these proteins to do measurements of RNA generation, for example, or of the translation of RNA to proteins,” says Edward ...
Here are three other fields where RNA is being investigated. Vaccines. The mRNA vaccines that are used to protect against SARS-CoV-2 (the virus that causes COVID-19) are the first of their kind to ...
In GEN’s initial A-List published in 2018, the top five public companies generated a combined $1.536 billion in revenues for 2017 and the first three quarters of 2018.By contrast, the top five ...
Illustrations of double-stranded DNA, RNA and a wormlike bead chain model. The radial distribution of the end-to-end distance, Ree, and contour length, L, are shown.
Once inside, the coronavirus releases a snippet of genetic material called RNA. Viral protein. Viral RNA. Hijacking the Cell. The virus’s genome is less than 30,000 genetic “letters” long.
Small interfering RNA bound to a messenger RNA, illustration model with semi-transparent surface. siRNAs are synthetic RNA interference tools used for inducing temporary reduction of mRNA expression.