The Buffalo Bills will play the San Francisco 49ers at home at Highmark Stadium on "Sunday Night Football" in Week 13. The ...

San Francisco 49ers quarterback Brock Purdy missed last week's game against the Green Bay Packers. Will he play against the ...

Here are the full injury reports for the Buffalo Bills and San Francisco 49ers ahead of their Week 13 matchup at Highmark ...

One of the top receivers in the league will be featured when George Kittle and the San Francisco 49ers visit the Buffalo ...

While the 49ers look like an easy opponent, San Francisco's health could be a major factor in the game, warns one NFL expert.

See who's in and who's out for the Week 13 matchup between the Buffalo Bills and San Francisco 49ers on December 1, 2024.

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

The San Francisco 49ers may again be without starting quarterback Brock Purdy for their Week 13 clash with the San Francisco ...

The Buffalo Bills Sunday night game against the San Francisco 49ers is shaping up to be a weather game as bitter cold air ...