With playoff aspirations, the San Francisco 49ers prepare to face the Buffalo Bills. Defensive end Leonard Floyd stresses the ...

In a season where running backs are thriving in the NFL, the 49ers hope to get Christian McCaffrey back on track.

Speaking with reporters on Wednesday, San Francisco 49ers head coach Kyle Shanahan says it's "unfair" to expect running back ...

San Francisco 49ers running back Christian McCaffrey is three games into his return from injury. The two-time first-team ...

The 49ers have sure had their fair share of struggles over the years, and head coaching carousel’s were constantly at the ...

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

The 49ers got blown out by the Packers in Week 12 and rookie wideout Ricky Pearsall was held without a catch for the second ...

The San Francisco 49ers' 2024 season has not gone according to plan. After a trip to and gut-wrenching defeat in Super Bowl ...

The 49ers happened to have room at quarterback amid Brock Purdy's injury. Kyle Shanahan revealed if Daniel Jones was a ...

Christian McCaffrey has been inefficient in his three games played since dealing with Achilles tendinitis. He doesn't look ...

They have a tough game in Buffalo on Sunday night. A loss would further complicate their path to the postseason.So how is ...

San Francisco 49ers head coach Kyle Shanahan confirmed Wednesday that the team discussed the possibility of signing ...