There was a clarifying moment late in Wednesday’s two-and-a-half-hour-long oral argument in United States v. Skrmetti, a history-making challenge to Tennessee’s ban on gender-affirming care for minors.

The Supreme Court will hear oral arguments Wednesday over Tennessee’s ban on gender-affirming care for minors, a landmark case that will have implications nationwide as Republicans have increasingly targeted transgender rights and enacted bans on healthcare for minors across the country.

The ruling could set a precedent for several challenges to state laws regarding sports participation, bathroom use and health care for adults.