Scientists say they captured 3D images of a new organelle they're calling a "hemifusome," which may be a recycling center in ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can ...

In the world of viral research, uncovering a virus’s weaknesses is often a painstaking process that requires years of ...

Recent epigenetics research has demonstrated that chromatin conformation plays an important role in various aspects of gene regulation. Chromosome Conformation Capture (3C) technology makes it ...

This enables figuring out the 3D architecture of DNA molecules, ... At the same time, this is a new approach to the study of chromatin structure, ...

Harvard University researchers at the Broad Institute report that expansion in situ genome sequencing (ExIGS) linked nuclear abnormalities to hotspots of aberrant chromatin regulation, potentially ...

The three-dimensional (3D) chromatin structure of Epstein–Barr virus (EBV) within host cells and the underlying mechanisms of chromatin interaction and gene regulation, particularly those involving ...

Chinese researchers have developed a technology that sheds light on how the three-dimensional (3D) organization of plant genomes influences gene expression—especially in photosynthesis.

“We are finding the 3D structure of the genome,” said Satoshi Namekawa, PhD, ... “CTCF-mediated 3D chromatin sets up the gene expression program in the male germline. ...

In a paper published on aBIOTECH, the authors revealed the joint regulation of chromatin structure and gene expression by BMI1s, the core components of Arabidopsis PRC1, and the condensin complexes.

Inside the cell nucleus, DNA and proteins form a complex called chromatin, which has several levels of organization, allowing cells to cram 2 meters of DNA into a nucleus that is only one-hundredth of ...