It has been known for several years that abnormal chromosome numbers lead to protein imbalances in the affected cells.

David Ussery discusses using Machine Learning methods to predict the pathogenicity of a bacterial infection based on genome ...

It would be interesting to explore the shifts in proteome/transcriptome composition to see whether any genes particularly affected by restricted genome concentration are also especially sensitive to ...

Figure 1: The Quaternary Structural Proteome Atlas of a CEll is a genome-scale annotation platform that was applied to the E. coli proteome. (a) The QSPACE platform requires two user-defined inputs: a ...

Multiomics is a multidisciplinary, holistic approach to biological analysis in which scientists integrate and analyze different types of omics data from a single sample. 1 The omes commonly featured ...

Phosphorylation is the most studied post-translational modification, and has multiple biological functions. In this study, we have reanalyzed publicly available mass spectrometry proteomics data sets ...

For the last 3 decades, the curiosity of molecular biologists has been to understand the long-neglected grey areas of our genome and proteome. A majority of the human DNA was considered "junk DNA" as ...

Moving beyond the genome, we will start to gain more clinical insights into the impact of protein modifications, abundance and localisation. This is particularly true when considering the development ...

Beyond the genome, protection of our proteome – that is to say, our proteins – can now be seen as the key to our health and longevity. This article was originally published in French.