In biology textbooks and beyond, the human genome and DNA therein typically are taught in only one dimension. While it can be ...

Investigating how mutations in tumors alter DNA’s 3D structure—and subsequently, regulatory sequences called enhancers—can offer new treatment opportunities.

He has a background in physics and engineering. He works as a bioinformatics technician in the structural genomics team of Marc A. Martí-Renom at CNAG-CRG (Barcelona), developing tools for the ...

Summary: Arima-HiC services is selected by the prestigious G10K consortium to generate ‘near-gapless’ reference genome assemblies for all vertebrate order species (phase 1).In a second related ...

SAN DIEGO--(BUSINESS WIRE)--Arima Genomics, Inc., a biotechnology company accelerating the adoption of the genome structure information, announced today that its new high-coverage HiC technology ...

While Hi-C reveals a great deal about the overall 3D organization of the genome, it has limited resolution to pick out specific interactions between genes and regulatory elements such as enhancers.

Scientists have taken whole genome sequencing to the next level by creating a 3D map of the genome to better understand development and disease. Like pirates on a treasure hunt, St. Jude Children ...

The discoveries could also help scientists working on stem cell therapies, since coaxing a stem cell to become a neuron or heart cell requires shifting it from one genetic program to another — each ...