DNA can be thought of as a vast library that stores all genetic information. Cells do not use this information all at once. Instead, they copy only the necessary parts into RNA, which is then used to ...

The AHA recommended whole exome or whole genome sequencing as first-line diagnostic tools for mitochondrial diseases.

Metabolism, far from being just a housekeeping function, underlies all changes in cell size and function ...

Itaconate, an endogenous mitochondrial metabolite produced by the enzyme aconitate decarboxylase 1 (ACOD1), has emerged as a central regulator of ...

1 Department of Obst & Gynecology, Shadan Institute of Medical Sciences, Medical Health and Research Institute (MHRI), Hyderabad, India. 2 Centre for Liver Research and Diagnostics-DCMS, CMH Research ...

ABSTRACT: Transcription factors play a critical regulatory role in the occurrence and development of malignant tumors. MAZ (MYC-Associated Zinc finger protein), as an important transcriptional ...

Mitochondria are involved in apoptosis, necrosis, pyroptosis, and iron death. At present, the research on cell apoptosis is relatively thorough, and the mechanism of mitochondria in it has also been ...

The Key Lab of Guizhou Provincial Department of Education for Medical Prevention and Treatment of Tumor, Zunyi Medical University, Zunyi, Guizhou 563000, China Institute of Life Sciences, Zunyi ...

Inhibition of mitochondrial RNA polymerase (POLRMT) drives significant weight loss and improved metabolic markers in obese mouse models. Findings underscore the promise of targeting mitochondrial ...