The SUBITO trial, presented by Rianne L Seefat and colleagues in The Lancet Oncology,1 revisits the long-standing debate ...
The prognostic significance of homologous recombination repair gene (HRRg) mutations across the different metastatic prostate cancer stages remains unclear. This retrospective real-world study ...
GameSpot may receive revenue from affiliate and advertising partnerships for sharing this content and from purchases through links. The outdoors feels more dangerous than ever in Grounded 2, and many ...
Krista McCay is a writer specializing in video game guides and walkthroughs. She first entered the industry in 2022 while studying English at UC Santa Barbara and working part-time as an editor. It ...
Alterations in genes involved in homologous recombination repair (HRR) occur in approximately 20-25% of patients with metastatic prostate cancer and are associated with aggressive biology, poor ...
A whole-genome sequencing approach shows early promise over current commercial methods for identifying more patients likely to benefit from PARP inhibitor cancer treatments, according to a study led ...
Harry Aikines-Aryeetey has myostatin deficiency Getty Images; design: Kelsea Petersen “A blessing and a curse” is how Harry Aikines-Aryeetey describes the genetic quirk that means his body carries ...
RAD51-based assessment effectively identifies HER2-negative metastatic breast cancer patients likely to respond to olaparib, especially with BRCA1/2 or PALB2 variants. RAD51-low tumors showed a higher ...
When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key repair process called homologous recombination, the cell uses loops in its ...
The phase 3 AMPLITUDE trial evaluated the safety and efficacy of adding niraparib to abiraterone acetate plus prednisone in patients with mHSPC. Additional data from the phase 3 AMPLITUDE trial ...
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